Table 3. Recent retrospective studies reporting venous thromboembolism (VTE) among patients with anaplastic lymphoma kinase (ALK)-rearrangement non-small-cell lung cancer.
| Study | Sample size (n) | VTE | VTE rate (%) | ALK+ | VTE in ALK+ | VTE rate in ALK+ (%) | P value (χ2-test) | Pm |
|---|---|---|---|---|---|---|---|---|
| Verso et al. (17) | 173 | 18 | 24.7 | 17 | 8 | 47.1 | 0.003 | <0.001 |
| Davidsson et al. (18) | 293 | 53 | 18.1 | 48 | 13 | 27.1 | 0.242 | |
| Lee et al. (19) | 1,998 | 131 | 6.6 | 24 | 4 | 16.7 | 0.170 | |
| Alexander et al. (20) | 1,384 | – | – | 70 | 12 | 17.1 | – | |
| Zer et al. (21) | – | – | – | 55 | 23 | 41.8 | – | |
| – | – | – | 43 | 12 | 27.9 | – | ||
| Current study | 513 | 30 | 5.8 | 29 | 6 | 20.7 | 0.017 |
Pm, P value in merged cohort.