Table 3. Treatment-related adverse events.

Treatment-related adverse events	All grades, n (%)	Grade 3 or 4, n (%)
Any adverse event	29 (96.7)	14 (46.7)
Thrombocytopenia	16 (53.3)	5 (16.7)
Neutropenia	13 (43.3)	4 (13.3)
Proteinuria	4 (13.3)	3 (10.0)
Hypertension	9 (30.0)	3 (10.0)
ALT increased	7 (23.3)	1 (3.3)
AST increased	3 (10.0)	1 (3.3)
Diarrhea	3 (10.0)	1 (3.3)
Upper gastrointestinal hemorrhage	1 (3.3)	1 (3.3)
Hoarseness	7 (23.3)	1 (3.3)
Palmar-plantar erythrodysesthesia syndrome	14 (46.7)	1 (3.3)
Anorexia	4 (13.3)	0
Headache	3 (10.0)	0
Dizziness	2 (6.7)	0
Fatigue	2 (6.7)	0
Periodontal disease	1 (3.3)	0

ALT, alanine transaminase; AST, aspartate aminotransferase.