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. 2020 Oct;8(20):1308. doi: 10.21037/atm-20-6373

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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ZSCAN31 was down-regulated after TAZ knockdown and highly expressed in HCC tissues after surgical resection. (A) Determination of the expression level of ZSCAN31 in HCC cell line (HepG2) by reverse transcription-polymerase chain reaction and western blot. Data are expressed as mean ± standard deviation (SD). *, P<0.05. (B) Determination of the protein levels of TAZ in 83 clinical HCC samples. (C) Immunostaining of HCC samples in a tissue microarray with a monoclonal anti-ZSCAN31 antibody (up 40×, down 100×). TAZ, transcriptional coactivator with PDZ binding motif; ZSCAN31, SCAN domain-containing protein 31; HCC, hepatocellular carcinoma.