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. 2020 Oct;8(20):1308. doi: 10.21037/atm-20-6373

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Combination of TAZ and ZSCAN31 with a better prognostic value for HCC after surgical resection. (A) Comparison of the OS rates of 83 HCC patients after liver resection between the low- and high-ZSCAN31 groups. (B) Correlation between TAZ expression and ZSCAN31 expression in HCC tissues from 83 patients. (C) Relationship between OS and co-expression of TAZ and ZSCAN31. In group A (n=19), both TAZ and ZSCAN31 were expressed at low levels; in group B (n=24), either TAZ or ZSCAN31 was highly expressed; in group C (n=40), both TAZ and ZSCAN31 were highly expressed. (D) Co-immunoprecipitation assay confirms the protein binding between TAZ and ZSCAN31. TAZ, transcriptional coactivator with PDZ binding motif; ZSCAN31, SCAN domain-containing protein 31; HCC, hepatocellular carcinoma; OS, overall survival.