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. 2020 Oct;8(20):1296. doi: 10.21037/atm-20-5856

Figure 1.

Figure 1

Influence of miR-103a-3p interference on HMGB1 expression in OGD- stimulated BV2 cells. (A,B) Effect of OGD treatment time on the expression of miR-103a-3p and HMGB1 in BV2 microglial cells. (C) miR-103a-3p mimic and anti-miR-103a-3p mimic were successfully constructed. (D,E,F,G) The effects of miR-103a-3p mimic and anti-miR-103a-3p mimic on HMGB1 expression in BV2 microglial cells, respectively. (H,I,G,K) Effects of miR-103a-3p mimic and anti-miR-103a-3p mimic on HMGB1 expression in OGD-stimulated BV2 microglial cells, respectively (*, P<0.05, **, P<0.01, versus the control group; ##, P<0.01 versus the miR-103a-3p NC group or the anti-miR-103a-3p NC group). HMGB1, high mobility group box 1; OGD, oxygen-glucose deprivation.