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. 2020 Oct 30;11:549527. doi: 10.3389/fneur.2020.549527

Table 5B.

Abilities of the Helsinki Computed Tomography Score alone and a panel consisting of the Helsinki Computed Tomography, interleukin 10, and β-Amyloid isoform 1–40 in distinguishing patients with unfavorable outcome from patients with favorable outcome.

Markers (threshold to be classified as positive) % pAUC (95% CI) % Specificity (95% CI) % Sensitivity (95% CI)
HCTS HCTS (>1) 2.5 (1.2–4.6) 22.4 (12.2–34.7) 97.0 (90.9–100)
Panel HCTS (>4) + IL-10 (<0.48 pg/ml) + Aβ40 (>7.38 pg/ml) 3.4 (1.7–6.2) 59.2 (44.9–71.4) 90.9 (78.8–100)

Marker thresholds to detect patients with unfavorable outcome are presented in the second column. At least two markers need to exceed the threshold in order for the panel to be positive. In the figure, a value before the parenthesis indicates that at least two markers need to be positive (exceed the threshold) in the panel. Values in the parenthesis are the specificity and sensitivity of the panel.

HCTS, Helsinki Computerized Tomography Score; IL-10, interleukin 10; Aβ40, β-Amyloid isoform 1–40.