Table 5B.
Markers (threshold to be classified as positive) | % pAUC (95% CI) | % Specificity (95% CI) | % Sensitivity (95% CI) | |
---|---|---|---|---|
HCTS | HCTS (>1) | 2.5 (1.2–4.6) | 22.4 (12.2–34.7) | 97.0 (90.9–100) |
Panel | HCTS (>4) + IL-10 (<0.48 pg/ml) + Aβ40 (>7.38 pg/ml) | 3.4 (1.7–6.2) | 59.2 (44.9–71.4) | 90.9 (78.8–100) |
Marker thresholds to detect patients with unfavorable outcome are presented in the second column. At least two markers need to exceed the threshold in order for the panel to be positive. In the figure, a value before the parenthesis indicates that at least two markers need to be positive (exceed the threshold) in the panel. Values in the parenthesis are the specificity and sensitivity of the panel.
HCTS, Helsinki Computerized Tomography Score; IL-10, interleukin 10; Aβ40, β-Amyloid isoform 1–40.