TABLE 3.

Summary of recent progress in microbial biosynthesis of isoprenoid-derived advanced jet fuel candidates.

Microbial host	Feedstock	Terpene	Potential biojet fuel blendstock	Titer (mg/L)	Scale	Operation	References
E. coli	Glucose	Bisabolene	Bisabolane	912	50 mL Flask	Batch	Peralta-Yahya et al. (2011)
		Linalool	RJ-4	505	Flask	Batch	Mendez-Perez et al. (2017)
		Eucalyptol	Limonane	653	Flask	Batch	Mendez-Perez et al. (2017)
		Pinene	Pinene dimers/pinane	32	5 mL Flask	Batch	Sarria et al. (2014)
		Epi-isozizaene	Epi-isozizaane	728	4 L Flask	Batch	Liu et al. (2018)
		Pentalenene	Pentalenane	780	2.5 L Flask	Batch	Liu et al. (2018)
		α-Isocomene	α-Isocomane	78	Flask	Batch	Liu et al. (2018)
		Limonene	Limonene/limonane	1,290	Flask	Fed-batch	Wu et al. (2019)
	Pure glycerol	Farnesene	Farnesane	8740	7 L Bioreactor	Batch	You et al. (2017)
		Limonene	Limonene/limonane	3,600	3.1 L Bioreactor	Fed-batch	Rolf et al. (2020)
		Sabinene	Sabinane	2,650	5 L Bioreactor	Fed-batch	Zhang et al. (2014)
		Myrcene	2,6-dimethyloctane	58	50 mL Flask	Batch	Kim et al. (2015)
	Crude glycerol	Farnesene	Farnesane	2,830	7 L Bioreactor	Batch	You et al. (2017)
S. cerevisiae	1.8% galactose/0.2% glucose	Bisabolene	Bisabolane	994	5 mL Flask	Batch	Peralta-Yahya et al. (2011)
		Pentalenene	Pentalenane	344	5 mL Flask	Batch	Liu et al. (2018)
	Unrefined cane syrup	Farnesene	Farnesane	130,000	200,000 L Bioreactor	Fed-batch	Meadows et al. (2016)
Y. lipolytica	Glucose	Farnesene	Farnesane	2,555	1 L Bioreactor	Batch	Liu Y. et al. (2019)
	Glycerol	Limonene	Limonene/limonane	165	1.5 L Bioreactor	Fed-batch	Cheng et al. (2019)
	Waste cooking oil	Limonene	Limonene/limonane	2.5	Flask	Batch	Pang et al. (2019)
		Bisabolene	Bisabolane	973	250 mL Flask	Batch	Zhao et al. (2020)
R. toruloides	Corn stover hydrolysate	Eucalyptol	Limonane	35	2 L Bioreactor	Batch	Zhuang et al. (2019)
		Bisabolene	Bisabolane	680	2 L Bioreactor	Fed-batch	Yaegashi et al. (2017)
Synechocystis sp.	CO2	Bisabolene	Bisabolane	22	3 L Photobioreactor	Batch	Sebesta and Peebles (2020)
		Limonene	Limonene/limonane	6.7	250 mL Flask	Batch	Lin et al. (2017)