Table 1.

Clinical Characters of the Fifteen Patients with RESLES.

Patient no.	Sex/ age	CNS manifestations	Presumed etiology	Associated drugs	Therapy	Inpatient/ outpatient	Hospital stays	mRS (up to 3m)
1	m/48	Sluggish in consciousness	Pneumonia	Piperacillin and tazobactam	Ceftriaxon, arithromycin (moxifloxacin)	Inpatient	11	0
2	m/43	Disarthria	Suspected hyponatremia	None	Clopidogrel,	Outpatient	0
3	m/44	Seizure, drowsiness and amnesia	Hypoglycemia	Gliclazide, dimethyldiguanide 250 mg.bid	50% dextrose, potassium chloride, aspirin, atorvastatin	Inpatient	8	1
4	m/35	Headache	Infection	acyclovir, acetaminophen	saline	Inpatient	9	0
5	f/25	Seizure, confused consciousness	Hyporexia hyponatremia	None	Saline, acyclovir, levetiracetam	Outpatient		0
6	f/40	Headache	postpartum, Pulmonary embolism	None	Warfarin	Inpatient	11	0
7	f/24	Recurrent seizure	levetiracetam	Levetiracetam	Levetiracetam	Outpatient	0
8	m/23	Paroxysmal blurred vision	bacterial respiratory infection	Levofloxacin, acetaminophen	Levofloxacin, Aspirin, atorvastatin	Inpatient	10	0
9	m/23	Dizziness with nausea and vomiting	Rabies vaccine injection	rabies vaccine, Amoxicillin and paracetamol	Ofloxacin, betahistine	Outpatient		0
10	m/25	Dizziness, paresthesia, dysmetria, memory problem, proxysmal vertigo, motor fine skills deficit	Hyperglycemia	None	Aspirin, atorvastatin, insulin, metformin	Inpatient	5	0
11	f/43	None	Carbamazepine		Cabamazepine	Outpatient	0	0
12	f/22	Hedache, loss of consciousness	Valproate/seizure	Valproate	Valproate	Inpatient	4	0
13	m/25	Dizzy, Paroxysmal blurred vision, unstable walk	Unknown	None	Aspirin	Outpatient	0	0
14	m/30	None	Presumed virus infection	None	Amoxicillin, ceftriaxone, levofloxacin, piperacillin and tazobactam, linezolid, compound paracetamol, indomethacin	Inpatient	8	0
15	m/53	Convulsion	Seizure	None	None	Outpatient	0	0

RESLES: reversible splenial lesion syndrome, Patient no.: patient number, m: male, f:female, CNS: central nervous system, mRS: modified Rankin Scale