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. 2020 Jun 30;59(20):2471–2480. doi: 10.2169/internalmedicine.4516-20

Table 4.

Etiologies of MERS and RESLES Type 1 and 2.

RESLES type 1 RESLES type 2
MERS type 1 MERS type 2
Infection Infuenza B (24), rotavirus, herpes virus-6 (24), Epstein-Barr virus (24), puumala hantavirus (50), mumps virus (26) Infuenza A (9, 59), VZV (25), adenovirus (63), nonfulminant hepatitis A (62), klebsiella pneumoniae (46), meningococcal meningitis (12), Mycoplasma pneumoniae (26, 27, 41, 46, 56), legionella pneumophila (37), tick-bites (38) Epstein-Barr virus (64, 67)
Seizures Seizure (71)
Drug Ipilimumba (57), sympathomimetic (55), minocycline (51)
Use of AEDs Phenytoin (1, 52), carbamazepine (3), vigabatrin (52) Olanzapine (7)
withdrawal of AEDs Valproate (26), oxcarbazepine (5, 33), topiramate (30), levetiracetam (34), phenytoin (3, 42), carbamazepine (72) Oxcarbazepine (33)
Autoimmune disease Anti-Yo rhombencehhalitis (39)
Metabolic disturbances Hypoglycemia (40, 48), methyl bromide poisoning (43), glufosinate ammonium poisoning (15), anorexia nervosa (73) Amanita phalloides intoxication (61), hemolytic uremic syndrome (44) Carbon monoxide poisoning (26), hypoglycemia (26, 70), MBD (26), osmotic myelinolysis (13)
Miscellaneous conditions cerebral venous thrombus (22), Anti-VGKC autoantibody syndrome (21), Charcot-Marie-Tooth disease (74), blood transfusion (49), migraine with aura (75)

Notes: All etiologies in MERS column also be etiologies of RESLES but are not listed in RESLES column now. MERS: mild encephalitis with a reversible splenial lesion syndrome, AEDs: antiepileptic drugs, VZV: varicella zoster virus, VGKC: voltage-gated potassium channel, MBD: Marchiafava-Bignami disease