Table 1.

mFOLFOX6+Bev Regimen and SOX+Bev Regimen.

Table 1a
mFOLFOX6+Bev (repeated every 2 weeks)
Rp.1	Palonosetron	iv	0.75 mg	15 min
	Dexart® injection		6.6 mg
	Sarine		50 mL
Rp.2	Bevacizumab	iv	5 mg/kg	90 min
	Sarine		100 mL	(after the second time 60 min→30 min)
Rp.3-1	Leucovorin	iv	200 mg/m2	120 min
	5% glucose solution		250 mL
Rp.3-2	Oxaliplatin	iv	85 mg/m2	120 min (co-administration with l-levofolinate)
	5% glucose solution		250 mL
Rp.4	Fluorouracil	bolus	400 mg/m2	bolus
	Sarine		50 mL
Rp.5	Fluorouracil	civ	2,400 mg/m2	46 h
	Sarine		total 230 mL
Table 1b
SOX+Bev (repeated every 3 weeks)
Rp.1	Palonosetron	iv	0.75 mg	15 min
	Dexart® injection		6.6 mg
	Sarine		50 mL
Rp.2	Bevacizumab	iv	7.5 mg/kg	90 min
	Sarine		100 mL	(after the second time 60 min→30 min)
Rp.3	Oxaliplatin	iv	130 mg/m2	120 min
	5% glucose solution		250 mL
Rp.4	Sarine	iv	50 mL	15 min
oral cytotoxic agents	S-1	po	40-60 mg according to body surface area	twice daily for 2 weeks

iv: intravenous injection, bolus: bolus injection, civ: continuous intravenous injection, po: per os