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Block diagram depicting key aspects of our theoretical vaccination model. An injection of peptide vaccine is given intramuscularly with adjuvant. Immature DCs are injected intranodally, prompting an accumulation of antigen by maturing DCs. These maturing DCs then migrate and activate naive T cells in the lymph node, which then proliferate into effector T cells. Effector T cells can both strip peptides off the surface of cancer cells via trogocytosis and kill cancer cells.
