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. 2020 Oct 30;12:578742. doi: 10.3389/fnagi.2020.578742

TABLE 3.

Characteristics of the participants with and without MCI stratified by sex (n = 4,631).

Characteristics Males (n = 2,052)
P-valuea Females (n = 2,579)
P-value
No Yes No Yes
No. of subjects 1,890 162 2,273 306
Sociodemographic characteristics
Age group (%, years)c
60–64 572 (30.3) 52 (32.1) 0.63 751 (33.0) 89 (29.1) 0.17
65–69 656 (34.7) 44 (27.2) 0.053 845 (37.2) 88 (28.8) <0.01
70–74 451 (23.9) 43 (26.5) 0.44 491 (21.6) 84 (27.5) 0.021
≥ 75 211 (11.2) 23 (14.2) 0.24 186 (8.18) 45 (14.7) <0.001
Education level (≥ high school,%) 478 (25.3) 35 (21.6) 0.30 229 (10.1) 16 (5.23) <0.01
Currently married (%) 1,704 (90.2) 136 (84.0) 0.014d 1,969 (86.6) 258 (84.3) 0.27
Income status (%, RMB)
<3,000 1,259 (66.6) 113 (69.8) 0.42 1,733 (76.2) 250 (81.7) 0.034
3,000–5,000 295 (15.6) 29 (17.9) 0.44 297 (13.1) 32 (10.5) 0.20
>5,000 336 (17.8) 20 (12.4) 0.082 243 (10.7) 24 (7.8) 0.13
Employed (%) 206 (10.9) 15 (9.26) 0.52 81 (3.56) 4 (1.31) 0.047
Health-related variables
BMI (kg/m2) 25.4 (25.3, 25.6)b 25.1 (24.7, 25.6) 0.19 25.7 (25.5, 25.8) 24.9 (24.6, 25.3) <0.001
Hypertension (%) 954 (50.5) 102 (63.0) <0.01 1,212 (53.3) 180 (58.8) 0.070
SBP (mmHg) 133.1 (132.5, 133.7) 134.6 (132.7, 136.6) 0.14 131.9 (131.3, 132.4) 134.6 (133.1, 136.1) <0.001
DBP (mmHg) 81.4 (81.0, 81.7) 81.9 (80.7, 83.0) 0.43 79.9 (79.6, 80.2) 79.9 (79.0, 80.7) 0.98
Diabetes (%) 319 (16.9) 30 (18.5) 0.59 442 (19.5) 59 (19.3) 0.95
FBG (mmol/L) 5.33 (5.28, 5.38) 5.21 (5.04, 5.37) 0.18 5.34 (5.30, 5.39) 5.22 (5.10, 5.35) 0.078
Hyperlipidemia (%) 994 (52.6) 85 (52.5) 0.98 1,660 (70.0) 193 (63.1) <0.001
TC (mmol/L) 4.85 (4.80, 4.90) 4.87 (4.71, 5.04) 0.77 5.30 (5.26, 5.35) 5.26 (5.13, 5.38) 0.49
TG (mmol/L) 1.24 (1.21, 1.27) 1.26 (1.17, 1.36) 0.66 1.57 (1.54, 1.60) 1.40 (1.32, 1.47) <0.0001
LDL-C (mmol/L) 2.36 (2.33, 2.39) 2.43 (2.33, 2.54) 0.15 2.58 (2.55, 2.61) 2.62 (2.54, 2.70) 0.32
HDL-C (mmol/L) 1.26 (1.24, 1.28) 1.24 (1.19, 1.30) 0.52 1.30 (1.29, 1.31) 1.32 (1.29, 1.36) 0.12
GS (adjusted weight) (kg) 31.3 (30.8, 31.7) 28.9 (27.6, 30.3) <0.0001 18.1 (17.8, 18.3) 16.0 (15.4, 16.6) <0.0001
PA(≥ 23.0 METs-h/w,%) 1,235 (65.3) 91 (56.2) 0.020 1,465 (64.5) 174 (56.9) <0.01
Sleepiness (scores) 9.32 (9.18, 9.45) 10.4 (9.85, 10.9) <0.0001 9.35 (9.22, 9.48) 9.85 (9.49, 10.22) <0.01
Sleep duration (%)
<6.5 h 121 (6.40) 9 (5.56) 0.67 142 (6.25) 14 (4.58) 0.25
6.5–8.5 h 1,072 (56.7) 79 (48.8) 0.051 1,194 (52.5) 123 (40.2) <0.0001
>8.5 h 697 (36.9) 74 (45.7) 0.027 937 (41.2) 169 (55.2) <0.0001
Smoking status (%)
Non-smoker 707 (37.4) 57 (35.2) 0.57 1,941 (85.4) 259 (84.6) 0.73
Ex-smoker 286 (15.1) 16 (9.88) 0.075 50 (2.20) 5 (1.63) 0.52
Current smoker 898 (47.5) 89 (54.9) 0.071 282 (12.4) 42 (13.7) 0.51
Alcohol drinking (%) 981 (48.1) 92 (43.2) 0.23 2,210 (2.77) 298 (2.61) 0.87
MMSE scores 27.2 (27.1, 27.3) 20.7 (20.4, 21.1) <0.0001 24.8 (24.6, 25.0) 16.4 (16.1, 16.8) <0.0001
ADL scores 15.2 (15.0, 15.3) 15.0 (14.5, 15.5) 0.40 15.7 (15.5, 15.8) 16.0 (15.5, 16.4) 0.19

BMI, body mass index; TC, total cholesterol; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBG, fasting blood glucose; GS, grip strength; PA, physical activity; METs, metabolic equivalents; MMSE, Mini-Mental State Examination; ADL, activities of daily living. aAnalysis of variance or logistic regression analysis. bGeometric least square mean (95% confidence interval) (all such values). cCategorical variables are expressed as number (percentage) of participants. dBoldface indicates statistical significance (P < 0.05) (or appropriate value).