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. 2020 Oct 30;12:578742. doi: 10.3389/fnagi.2020.578742

TABLE 5.

Association between the risk factors and MCI (adjusted ORs and 95% confidence intervals; n = 4,631).

Variables Age and sex adjusted
Multivariable adjustedb
OR (95%CI) P-valuea OR (95%CI) P-value
Sociodemographic characteristics
Age group (years)
60–64 1.00 (reference) 1.00 (reference)
65–69 0.83 (0.64, 1.06) 0.13 0.74 (0.58, 0.96) 0.021
70–74 1.29 (1.00, 1.66) 0.052 1.00 (0.76, 1.30) 0.98
≥75 1.67 (1.22, 2.27) <0.01c 1.20 (0.86, 1.67) 0.28
P for trenda <0.001 0.25
Females vs. males 1.61 (1.32, 1.97) <0.0001 1.11 (0.83, 1.49) 0.47
High school and above 0.68 (0.49, 0.92) 0.014 0.81 (0.58, 1.13) 0.23
Income status (RMB)
<3,000 1.00 (reference) 1.00 (reference)
3,000–5, 000 0.90 (0.67, 1.19) 0.46 1.14 (0.84, 1.53) 0.39
>5,000 0.69 (0.49, 0.94) 0.024 0.94 (0.65, 1.33) 0.71
P for trend 0.02 >0.99
Married vs. unmarried 0.81 (0.62, 1.07) 0.12 0.87 (0.67, 1.16) 0.34
Working vs. no work 0.72 (0.43, 1.13) 0.17 0.69 (0.41, 1.10) 0.14
Health-related variables
PA (METs-h/w) (≥23.0 vs. <23.0) 0.72 (0.60, 0.88) <0.01 0.79 (0.64, 0.96) 0.018
Smoking status
Non-smoker 1.00 (reference) 1.00 (reference)
Ex-smoker 0.69 (0.42, 1.10) 0.13 0.65 (0.39, 1.03) 0.077
Current smoker 1.20 (0.94, 1.52) 0.15 1.21 (0.94, 1.56) 0.14
P for trend 0.16 0.15
Alcohol drinking 0.86 (0.64, 1.16) 0.32 0.85 (0.62, 1.16) 0.31
Sleep duration (h)
<6.5 h 0.98 (0.61, 1.50) 0.91 0.94 (0.58, 1.46) 0.83
6.5–8.5 h 1.00 (reference) 1.00 (reference)
>8.5 h 1.56 (1.28, 1.90) <0.0001 1.40 (1.14, 1.72) <0.01
P for trend <0.001 0.006
Sleepiness (scores) 1.86 (1.41, 2.44) <0.0001 1.80 (1.36, 2.37) <0.0001
BMI (kg/m2) 0.95 (0.92, 0.98) <0.001 0.92 (0.89, 0.95) <0.0001
GS(per body weight) (kg/kg) 0.54 (0.41, 0.71) <0.0001 0.50 (0.38, 0.67) <0.0001
Hypertension 1.37 (1.12, 1.67) <0.01 1.44 (1.18, 1.77) <0.001
Diabetes 1.03 (0.80, 1.31) 0.79 1.01 (0.78, 1.30) 0.92
Hyperlipidemia 0.75 (0.62, 0.92) <0.01 0.83 (0.67, 1.02) 0.070

BMI, body mass index; GS, grip strength; PA, physical activity; METs, metabolic equivalents. aObtained by using multiple logistic regression analysis. bAdditionally adjusted for education level, income status, marriage status, employment status, physical activity, smoking status, drinking status, sleep duration, BMI, GS, hypertension, diabetes, hyperlipidemia, sleepiness. cBoldface indicates statistical significance (P < 0.05) (or appropriate value).