TABLE 7.
Association between the risk factors and MCI after excluding participants who had changed their lifestyle in the past 5 years (adjusted ORs and 95% CIs; n = 4,242).
| Variables | Age and sex adjusted |
Multivariable adjustedb |
||
| OR (95%CI) | P-valuea | OR (95%CI) | P-value | |
| Sociodemographic characteristics | ||||
| Age group (years) | ||||
| 60–64 | 1.00 (reference) | – | 1.00 (reference) | – |
| 65–69 | 0.81 (0.62, 1.04) | 0.10 | 0.73 (0.56, 0.94) | 0.017 |
| 70–74 | 1.24 (0.95, 1.61) | 0.11 | 0.96 (0.73, 1.27) | 0.78 |
| ≥75 | 1.69 (1.22, 2.31)c | <0.01 | 1.20 (0.85, 1.69) | 0.29 |
| P for trenda | < 0.001 | 0.31 | ||
| Females vs. males | 1.67 (1.36, 2.07) | <0.0001 | 1.18 (0.87, 1.60) | 0.29 |
| High school and above | 0.68 (0.49, 0.92) | 0.016 | 0.82 (0.57, 1.15) | 0.25 |
| Income status (RMB) | ||||
| <3,000 | 1.00 (reference) | – | 1.00 (reference) | – |
| 3,000–5,000 | 0.93 (0.69, 1.24) | 0.63 | 1.19 (0.87, 1.60) | 0.26 |
| >5,000 | 0.68 (0.48, 0.95) | 0.029 | 0.94 (0.64, 1.35) | 0.74 |
| P for trend | 0.035 | 0.90 | ||
| Married vs. unmarried | 0.82 (0.62, 1.09) | 0.16 | 0.88 (0.66, 1.18) | 0.38 |
| Working vs. no work | 0.71 (0.42, 1.14) | 0.18 | 0.68 (0.40, 1.10) | 0.14 |
| Health-related variables | ||||
| PA (METs × h/w) (≥23.0 vs. <23.0) | 0.76 (0.62, 0.93) | <0.01 | 0.81 (0.66, 1.00) | 0.049 |
| Smoking status | ||||
| Non-smoker | 1.00 (reference) | – | 1.00 (reference) | – |
| Ex-smoker | 0.63 (0.35, 1.06) | 0.098 | 0.61 (0.34, 1.04) | 0.087 |
| Smoker | 1.18 (0.92, 1.52) | 0.19 | 1.21 (0.93, 1.57) | 0.16 |
| P for trend | 0.20 | 0.17 | ||
| Alcohol drinking | 0.92 (0.67, 1.25) | 0.58 | 0.92 (0.66, 1.26) | 0.59 |
| Sleep duration (h) | ||||
| <6.5 h | 0.93 (0.57, 1.46) | 0.76 | 0.90 (0.54, 1.42) | 0.66 |
| 6.58.5 h | 1.00 (reference) | – | 1.00 (reference) | – |
| >8.5 h | 1.52 (1.24, 1.87) | <0.0001 | 1.37 (1.11, 1.70) | <0.01 |
| P for trend | <0.001 | <0.01 | ||
| Sleepiness (scores) | 1.79 (1.34, 2.39) | <0.0001 | 1.72 (1.28, 2.30) | <0.001 |
| BMI (kg/m2) | 0.95 (0.92, 0.98) | <0.001 | 0.93 (0.89, 0.96) | <0.0001 |
| GS (per body weight) (kg/kg) | 0.51 (0.39, 0.68) | <0.0001 | 0.47 (0.35, 0.64) | <0.0001 |
| Hypertension | 1.35 (1.11, 1.66) | <0.01 | 1.44 (1.16, 1.78) | <0.001 |
| Diabetes | 0.99 (0.76, 1.28) | 0.96 | 0.98 (0.75, 1.27) | 0.89 |
| Hyperlipidemia | 0.71 (0.58, 0.88) | <0.01 | 0.79 (0.64, 0.98) | 0.031 |
BMI, body mass index; GS, grip strength; PA, physical activity; METs, metabolic equivalents. aObtained by using multiple logistic regression analysis. bAdditionally adjusted for education level, income status, marriage status, employment status, physical activity, smoking status, drinking status, sleep duration, BMI, GS, hypertension, diabetes, hyperlipidemia, sleepiness. cBoldface indicates statistical significance (P < 0.05) (or appropriate value).