TABLE 2.

Unadjusted bivariate correlations between predictors, outcomes, and a priori covariates in the overall sample.

	Global cognition	White matter hyperintensities (WMH)	Fractional anisotropy (FA)	Mean diffusivity (MD)	Myelin water fraction (MWF)
IL-6	−0.281	–0.052	–0.044	0.021	–0.021
CRP	–0.064	–0.113	−0.256	–0.025	−-0.239
IL1-β	0.064	–0.117	0.138	–0.163	0.095
Age	–0.040	−0.425	–0.193	−-0.347	–0.188
Sex	0.203	–0.022	–0.228	–0.210	–0.066
Race	−-0.357	0.112	–0.183	–0.226	–0.154
pVIQ derived from Word Reading	−0.502	–0.127	0.084	0.086	0.044
FSRP-10	–0.085	−0.374	–0.164	–0.213	–0.171
ICV	−	0.174	0.214	0.244	0.049

Values are Pearson correlation (continuous) or point-biserial correlation (dichotomous) r-values. IL-6, Interleukin-6; CRP, C-reactive protein; IL1-β, Interleukin 1-beta; pVIQ, predicted verbal intelligence quotient derived from Word Reading, i.e., the Wechsler Test of Adult Reading; FSRP-10, Framingham Stroke Risk Profile 10 year percent risk of stroke; ICV, Intracranial Volume. Bolded entries indicate significance at or below a p-value of 0.05.