FIGURE 2.

Antimicrobial efficacy of aPDT with SAPYR SA-PN-05 and of CHX toward A. naeslundii, S. mutans, and E. coli biofilms. All results are depicted as medians, 1st and 3rd quartiles on a log₁₀-scaled ordinate. L– represents dark groups; L+ represents irradiated groups. Relative CFU data [CFU (%)] with untreated control group (UC L–) set to 100% for all bacteria. Horizontal solid and dashed lines represent CFU-reductions of 3 log₁₀ and 5 log₁₀, respectively. (A) A. naeslundii upon treatment with SAPYR or SA-PN-05 for 20 min incubation and 10 min irradiation or with CHX for 30 min incubation (γ, 100% ∼ 2.3 × 10⁸); (B) S. mutans upon treatment with SAPYR or SA-PN-05 for 5 min incubation and 10 min irradiation or with CHX for 15 min incubation (γ, 100% ∼ 7.9 × 10⁸); (C) E. coli upon treatment with SAPYR or SA-PN-05 for 5 min incubation and 10 min irradiation or with CHX for 15 min incubation (γ,100% ∼ 1.5 × 10⁷); §, not measured. n = 6.