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. 2020 Oct 30;11:589364. doi: 10.3389/fmicb.2020.589364

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Copyright © 2020 Muehler, Rupp, Keceli, Brochhausen, Siegmund, Maisch, Hiller, Buchalla and Cieplik.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Luminescence measurements for ATP level upon treatment with aPDT using SAPYR or CHX. Depicted are medians, 1st and 3rd quartiles of bacteria treated with SAPYR or CHX. ATP concentration was normalized to corresponding OD measurements of samples after treatment and expressed as ATP (nM/OD₆₀₀) (A) A. naeslundii after 20 min incubation. (B) S. mutans after 5 min incubation. (C) E. coli after 5 min incubation. Yellow bars (L+) represent groups treated with SAPYR irradiated for 10 min. Gray bars (L–) represent dark controls or CHX, respectively. Asterisk depict statistical difference (p ≤ 0.05) among UC L– and treated groups. §, not measured. n = 4.