Table 1.
Sample Characteristics Derived From Baseline, If Not Stated Otherwise
| Total Sample, N = 1780 | Age ≤ 72, n = 1185 | Age ≥ 78, n = 595 | |
|---|---|---|---|
| Number of follow-up assessments | 3.0 (0.8) | 2.9 (0.6) | 3.2 (1.1) |
| Odor identification score, mean (SD) | 12.1 (2.8) | 12.8 (2.3) | 10.6 (3.1) |
| Age, mean (SD) | 71.0 (9.4) | 65.3 (4.8) | 82.5 (4.6) |
| Female % | 61.9 | 58.6 | 68.4 |
| Years of education, mean (SD) | 12.6 (4.2) | 13.5 (4.2) | 10.8 (3.8) |
| Manufacturing profession, % | 17.9 | 13.8 | 27.7 |
| Vocabulary (SRB1), mean (SD) | 23.5 (4.6) | 24.3 (4.1) | 21.8 (5.0) |
| History of cerebrovascular disease, % | 7 | 3.9 | 12.9 |
| Cardiovascular disease burden, mean (SD) | 0.3 (0.7) | 0.2 (0.5) | 0.6 (0.9) |
| Diabetes, % | 7.6 | 6.9 | 8.9 |
| Hypertension stage 2, % | 48.3 | 40.2 | 64.4 |
| Smoking, %: currently/ever/never | 13/41/46 | 15/44/41 | 9/35/56 |
| Obesity, % | 13.4 | 14.4 | 12.6 |
| Depression, % | 3 | 2 | 5.0 |
| History of head trauma, % | 13.3 | 14.9 | 9.9 |
| Number of medications, mean (SD) | 3.4 (3.1) | 2.8 (2.8) | 4.7 (3.3) |
| Gait speed, mean (SD) | 1.15 (0.4) | 1.3 (0.3) | 0.9 (0.4) |
| APOE ε4 carrier, % | 28.5 | 30.2 | 25.2 |
| BDNF met carrier, % | 33.5 | 33.6 | 33.3 |
| Development of dementia at follow-up, % | 14.0 | 6.0 | 29.9 |
Note: N = sample size. Percentage missing values: 0.1% for manufacturing profession, 0.5% for vocabulary, 0.1% for hypertension, 0.6% for smoking, 1.3% for obesity, 1.4% for gait speed, 1.4% for APOE, and 4.0% for BDNF.