Table 4.
The Rate Ratio of Hospitalizations for Different Categories of Illness (Based on the ICD-9 Classification) for the Total Cohort and Categorized by Sex Between Those With and Without Albuminuria From the Cardiovascular Health Study
| Category | All (n = 3,110) | Men (n = 1,276) | Women (n = 1,834) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Rate Ratio | 95% CI | p Value | Rate Ratio | 95% CI | p Value | Rate Ratio | 95% CI | p Value | |
| Infectious (n = 522) | 1.24 | 0.92, 1.68 | .15 | 0.93* 1 | 0.52, 1.64 | .79 | 1.47 | 1.03, 2.10 | .03 |
| Neoplasms (n = 621) | 1.12 | 0.74, 1.68 | .59 | 1.45 | 0.87, 2.43 | .16 | 0.82 | 0.43, 1.56 | .55 |
| Endocrine (n = 487) | 1.61 | 1.16, 2.25 | .005 | 1.18 | 0.64, 2.18 | .60 | 1.98 | 1.34, 2.91 | <.001 |
| Blood (n = 138) | 1.23 | 0.68, 2.23 | .49 | 0.53* 2 | 0.15, 1.87 | .23 | 1.76 | 0.90, 3.43 | .10 |
| Mental (n = 114) | 0.88 | 0.45, 1.72 | .71 | 0.21 | 0.04, 1.08 | .06 | 1.36 | 0.60, 3.08 | .46 |
| Nervous system (n = 199) | 1.08 | 0.64, 1.83 | .77 | 0.53*3 | 0.19, 1.51 | .23 | 1.80 | 1.02, 3.16 | .04 |
| Circulatory (n = 3,884) | 1.65 | 1.43, 1.91 | <.001 | 1.66 | 1.34, 2.05 | <.001 | 1.66 | 1.37, 2.02 | <.001 |
| Respiratory (n = 1,538) | 1.61 | 1.28, 2.04 | <.001 | 1.92 | 1.39, 2.65 | <.001 | 1.36 | 0.99, 1.87 | .06 |
| Digestive (n = 1,267) | 1.16 | 0.92, 1.48 | .23 | 1.11 | 0.76, 1.60 | .60 | 1.22 | 0.89, 1.68 | .22 |
| Genitourinary (n = 746) | 1.39 | 1.09, 1.77 | .008 | 1.09* 4 | 0.74, 1.64 | .67 | 1.74 | 1.26, 2.38 | <.001 |
| Skin (n = 191) | 1.06 | 0.63, 1.78 | .83 | 0.38* 5 | 0.12, 1.20 | .10 | 1.63 | 0.95, 2.80 | .08 |
| Musculoskeletal (n = 618) | 1.23 | 0.94, 1.61 | .13 | 1.06 | 0.67, 1.68 | .81 | 1.30 | 0.93, 1.82 | .13 |
| Symptoms (n = 998) | 1.13 | 0.89, 1.43 | .31 | 1.07 | 0.75, 1.55 | .70 | 1.18 | 0.86, 1.60 | .30 |
| Injury (n = 1,275) | 1.30 | 1.06, 1.59 | .01 | 1.42 | 1.00, 2.00 | .05 | 1.19 | 0.93, 1.53 | .17 |
| Cause of injury (n = 121) | 1.83 | 0.67, 5.04 | .24 | 1.44 | 0.22, 9.46 | .71 | 2.51 | 0.88, 7.15 | .09 |
Notes: Results are fully adjusted per Model 2, Table 3. Statistically significant results are in bold. The numbers next to the hospitalization category are the number of hospitalizations for that category in the total cohort. Starred results (*) are significant incident rate ratio (IRR) differences between men and women. Rates of incident hospitalization for all participants per 100 participant-years for those without and with albuminuria in each disease category are shown. Significant IRR differences between men and women (*) (1): 0.55 [0.31, 0.99], p = .05 (2); 0.20 [0.05, 0.81], p = .02 (3); 0.33 [0.12, 0.94], p = .04 (4); 0.62 [0.40, 0.98], p = .04; (5) 0.31 [0.10, 0.95], p = .04.
1. Infectious: 1.54 (1.37, 1.73) vs. 2.40 (1.84, 3.14).
2. Neoplasms: 1.94 (1.66, 2.26) vs. 2.26 (1.59, 3.20).
3. Endocrine: 1.22 (1.03, 1.46) vs. 3.42 (2.74, 4.26).
4. Blood: 0.41 (0.36, 0.53) vs. 0.59 (0.38, 0.93).
5. Mental: 0.37 (0.29, 0.47) vs. 0.36 (0.19, 0.67).
6. Nervous system: 0.63 (0.52, 0.77) vs. 0.65 (0.47, 0.92).
7. Circulatory: 10.40 (9.70, 11.54) vs. 23.71 (20.93, 26.85).
8. Respiratory: 4.29 (3.83, 4.80) vs. 8.42 (7.05, 10.04).
9. Digestive: 3.79 (3.42, 4.19) vs. 5.51 (4.61, 6.57).
10. Genitourinary: 2.12 (1.90, 2.37) vs. 3.86 (3.20, 4.66).
11. Skin: 0.55 (0.45, 0.68) vs. 0.93 (0.57, 1.52).
12. Musculoskeletal: 1.93 (1.75, 2.12) vs. 2.26 (1.78, 2.86).
13. Symptoms: 3.00 (2.73, 3.30) vs. 4.24 (3.59, 5.00).
14. Injury: 3.81 (3.51, 4.13) vs. 5.59 (4.60, 6.80).
15. Cause of injury: 0.33 (0.21, 0.51) vs. 0.72 (0.33, 1.58).