Table 10.
Publications found in the US National Library of Medicine National Institutes of Health (NCBI-PubMed) reporting the standardisation of the LAMP technique as a useful tool for diagnosing lymphatic filariasis in the definitive host.
| Parasite | Gene | Extracted/Spiked/Natural DNA | Sample | Sample Size | Sensitivity | Reference |
|---|---|---|---|---|---|---|
| B. malayi | Hha I repeat (BmHha I) | Natural DNA | Human blood samples | 8 | 1/100th of microfilaria (1 pg) | [126] |
| W. bancrofti | WbLDR | 1/5000th of microfilaria | ||||
| W. bancrofti | Nuclear scaffold/matrix attachment region | Natural DNA | Human blood samples | Blood: 3067 | ND | [127] |
| W. bancrofti | Nuclear scaffold/matrix attachment region | Natural DNA | Human blood samples | Blood: 3067 | ND | [128] |
| B. malayi or B. timori | Hha I repeat | Extracted/natural DNA | Feline blood samples | 1 | 0.001 ng | [129] |
| W. bancrofti | Nuclear scaffold/matrix attachment region | Extracted/spiked DNA | Human blood | - | 1/1000th of microfilaria | [130] |