Table 17.
Publications found in the US National Library of Medicine National Institutes of Health (NCBI-PubMed) reporting the standardisation of the LAMP technique as a useful tool for diagnosing soil-transmitted helminthiases (intestinal worms) in the definitive host.
| Parasite | Gene | Extracted/Spiked/Natural DNA | Sample | Sample Size | Sensitivity | Reference |
|---|---|---|---|---|---|---|
| T. trichiura | ITS-2 | Natural DNA | Human faeces | 137 | 98.6 × 10−9 ng/μL or a single egg | [172] |
| Strongyloides spp. | 18S rRNA | Natural DNA | Human urine | 24 | ND | [173] |
| A. lumbricoides | β-tubulin isotype 1 | Extracted/natural/spiked DNA | Human faeces | 21 | 1 pg or a single egg | [174] |
| T. trichiura | 15 | |||||
| N. americanus | 19 | |||||
| Strongyloides spp. | 18S rRNA | Extracted/natural DNA | Rat faeces and urine Human faeces |
12 | 10−3 ng | [175] |
| A. lumbricoides | ITS-1 | Natural DNA | Human faeces | 581 | 10.8 ng (equivalent to a single egg) | [176] |
| N. americanus | ITS-2 | Natural DNA | Human faeces | 106 | 0.4 fg | [177] |