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Molecular reporter system for ssRNA (−) genome virus detection. The principle of the reporter system is based on the production of mRNA without the cap and the polyA tail. Such RNAs mimic the virus genome. Ribozymes hydrolyze RNA or RNA-polymerase I promoters. This transcript mimics (−) viral RNA, which allows it to be replicated using viral proteins. The transcription of the reporter protein occurs from (+) RNA obtained in this manner.
