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. 2020 Oct 30;21(21):8145. doi: 10.3390/ijms21218145
NLRP3, 1, 6, 12 NOD-like receptor family pyrin domain-containing 3, 1, 6, 12
PRR Pattern recognition receptor
PAMP Pathogen-associated molecular pattern
DAMP Danger-associated molecular pattern
CAPS Cryopyrin-associated periodic syndrome
CARD Caspase recruitment domain
ASC Apoptosis-associated speck-like protein containing a caspase recruitment domain
IL Interleukin
NLR NOD-like receptor
PYD Pyrin domain
IBD Inflammatory bowel disease
KO Knockout
TLR Toll-like receptor
RLR Retinoic acid-inducible gene-I-like receptor
AIM2 Absent in melanoma 2
ALR Absent in melanoma 2-like receptor
PYHIN Pyrin and HIN domain
NLRC4 NOD-like receptor family caspase recruitment domain-containing 4
NACHT Neuronal apoptosis inhibitory protein, MHC class II transcription activator, incompatibility locus protein from Podospora anserina, and telomerase-associated protein
NAIP Neuronal apoptosis inhibitory protein
CIITA MHC class II transcription activator
HET-E Incompatibility locus protein from Podospora anserina
TP1 Telomerase-associated protein
LRR Leucine-rich repeat
NAIP Neuronal apoptosis inhibitory protein
IL-1R Interleukin-1 receptor
NF-κB Nuclear factor-kappa B
T3SS/T4SS Type III/IV secretion system
MDP Muramyl dipeptide
ROS Reactive oxygen species
BTK Bruton’s tyrosine kinase
JNK c-Jun N-terminal kinase
NEK7 NIMA-related kinase 7
TAK1 TGF-β-activated kinase 1
GBP5 Guanylate-binding protein 5
CaSR Calcium-sensing receptor
CD Crohn’s disease
LPS Lipopolysaccharide
FMF Familial Mediterranean fever
UC Ulcerative colitis
SNP Single-nucleotide polymorphism
TNF Tumor necrosis factor
Th T helper
DSS Dextran sulfate sodium
IFN Interferon
IL-18BP Interleukin-18-binding protein
NK Natural killer
IEC Intestinal epithelial cell
ATG Autophagy-related gene
Treg T regulatory
SCFA Short-chain fatty acid
PBMC Peripheral blood mononuclear cell
WT Wild type
AOM Azoxymethane
STAT Signal transducer and activator of transcription
TNBS 2,4,6-trinitrobenzene sulfonic acid