Table 1.

Equilibrium constants for hemin binding to Aβ₄₀.

Complex a	log K1	log K2 b	log β2
[hemin(Aβ40)2]	6.08 ± 0.02	4.77	10.84 ± 0.02
[hemin(Aβ40)2] c	5.60 ± 0.01	4.20	9.80 ± 0.01
[hemin(Aβ40)2] d	4.76 ± 0.03	4.30	9.05 ± 0.01
[hemin(Aβ40)2] e	5.30 ± 0.02	4.47	9.77 ± 0.04
[hemin(Aβ40)2] f	7.30 ± 0.02	4.02	11.32 ± 0.16
[hemin(Aβ16)2] g	4.80 ± 0.02	4.03	8.82 ± 0.02

^a Standard conditions: hemin (5 μM) in pH 7.4 phosphate buffer (5 mM) at 23 °C. ^b Obtained as the difference between log β₂ and log K₁. ^c pH 6.89. ^d pH 6.3. ^e 50 mM phosphate buffer pH 7.4. ^f 37 °C. ^g 50 mM PBS, pH 7.5, 27 °C; [13].