Table 1.
Antimicrobial molecules synthesized by B. velezensis to control pathogenic microbes.
| Compounds | Gene Clusters | Antimicrobial Activity | References | |||
|---|---|---|---|---|---|---|
| Antibacterial Activity (Diseases) | MIC (Pathogens) | Antifungal Activity (Diseases) | MIC (Pathogens) | |||
| Surfactins | SrfA-D | Cochliobolus carbonum (Leaf spot); P. syringae pv. tomato; R. solanacearum | 25-100 µg/mL (P. syringae pv. tomato) |
F. verticillioides (Maiz disease) |
- | [20,21,22,23] |
| Fengycins | FenA-E | R. solanacearum (Tomato wilt), X. euvesicatoria (Pepper spot); X. axonopodis pv. esicatoria | - | F. oxysporum (banana Fusarium wilt); F. graminearum (Fusarium head blight); B. cinerea (Grey mould); R. variabilis (Maiz disease) | 20.0 µg/mL (M. grisea); 100 µg/mL (F. graminearum) |
[2,24,25,26,27,28] |
| Bacillomycin-D | bmyA-D | X. campestris pv. cucurbitae | - | Colletotrichum gloeosporioides (Bitter rot); F. graminearum (Fusarium head blight); F. oxysporum f. sp. cucumerinum (Cucumber vascular wilt) | 30 μg/mL (F. graminearum) | [12,29,30,31] |
| Bacillaene | baeBCDE, acpK, baeGHIJLMNRS | E. amylovora (Fire blight) | - | Termitomyces spp. | - | [32,33] |
| Macrolactin | MlnA-I | S. aureus; B. cepacia | - | - | - | [34] |
| Difficidin | dfnAYXBCDEFGHIJKLM | X. oryzae pv. oryzae (Rice blight) and X. oryzae pv. oryzicola (Rice leaf streak); E. amylovora (Fire blight); R. solanacearum (Tomato wilt) | 12.62 μg/mL (R. solanacearum); | - | - | [32,35,36] |
| Bacilysin | bacA-E | S. aureus and C. michiganense; X. oryzae pv. oryzae (Rice blight) and X. oryzae pv. oryzicola (Rice leaf streak); E. amylovora (Fire blight) | 50.0 μg/mL (X. oryzae pv. oryzae and X. oryzae pv. oryzicola) | - | - | [32,35,37] |