Figure 1.
Immunofluorescent analysis of platelet endothelial cell adhesion molecule (PECAM-1) and lymphatic vessel endothelial hyaluronan receptor ( LYVE-1) staining in control mice (Cont), mice with dextran sulfate sodium (DSS)-induced colitis, and mice treated with DSS + artemisinin (Art). (a) The colon tissue was stained using PECAM-1 (red) and LYVE-1 (green), and PECAM-1/LYVE-1. Scale bar, 50 μm. PECAM+ LYVE-1− (red arrow) indicates the blood vessels, and PECAM+ LYVE-1+ indicates the lymphatic vessels (b) Quantification of the area of PECAM+ LYVE-1− blood vessels (c) Area with PECAM+ LYVE-1+ lymphatic vessels in colon tissue. Data shown are from three independent experiments and are expressed as mean ± SD (n = 10 per group); ## p < 0.01, DSS versus Cont; ** p < 0.01, DSS + Art versus DSS.