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. 2020 Nov 3;21(21):8212. doi: 10.3390/ijms21218212

Table 1.

Motor measures acquired in an open field and anxiety-like/motor measures acquired in a light-dark transition task from Tat(−) and Tat(+) males that were exposed (or not) to a 15-min forced swim stress prior to administration of saline or oxycodone. * indicates a main effect of genotype wherein Tat(+) mice differ from Tat(−) controls. † indicates a main effect for oxycodone to differ from saline administration, p ≤ 0.05.

Behavioral Measure Non-Stressed Stressed
Saline (0.9% w/v) Oxycodone (3 mg/kg) Saline (0.9% w/v) Oxycodone (3 mg/kg)
Tat(−) (n = 8–9) Tat(+) (n = 7–8) Tat(−) (n = 12) Tat(+) (n = 8–9) Tat(−) (n = 8) Tat(+) (n = 9) Tat(−) (n = 8) Tat(+) (n = 9)
Mean Velocity (m/s) 0.025 ± 0.004 0.027 ± 0.002 * 0.048 ± 0.008 0.076 ± 0.009 * 0.005 ± 0.001 0.002 ± 0.001 0.012 ± 0.003 0.015 ± 0.004
Rearing number 39.4 ± 6.2 23.8 ± 3.2 18.1 ± 11.4 6.8 ± 2.2 4.5 ± 2.4 0.9 ± 0.7 0.8 ± 0.3 0.7 ± 0.2
Rearing Time (s) 31.13 ± 4.74 20.31 ± 2.58 * 3.66 ± 1.56 2.14 ± 0.92 * 2.61 ± 1.53 0.63 ± 0.60 0.29 ± 0.15 0.19 ± 0.09
Latency to first enter dark (s) 61 ± 32 28 ± 19 14 ± 4 22 ± 9 77 ± 45 89 ± 36 63 ± 38 37 ± 33
Light zone time (s) 106 ± 32 17 ± 5 * 75 ± 17 43 ± 9 * 102 ± 40 121 ± 27 112 ± 32 30 ± 5
Number of transitions 9 ± 3 5 ± 1 * 13 ± 2 8 ± 1 * 9 ± 3 7 ± 1 13 ± 3 11 ± 3