Table 2.

Motor measures acquired in an open field and anxiety-like/motor measures acquired in a light-dark transition task from Tat(−) and Tat(+) males that were exposed (or not) to a 15-min forced swim stress with repeated administration of saline or oxycodone. * indicates a main effect of genotype wherein Tat(+) mice differ from Tat(−) controls. † indicates a main effect for oxycodone to differ from saline-administered mice. ‡ indicates an interaction wherein the denoted group significantly differs from Tat(+), saline-administered controls. § indicates an interaction wherein the denoted group significantly differs from all other groups, p ≤ 0.05.

Behavioral Measure	Non-Stressed				Stressed
	Saline (0.9% w/v)		Oxycodone (3 mg/kg)		Saline (0.9% w/v)		Oxycodone (3 mg/kg)
	Tat(−) (n = 8)	Tat(+) (n = 10)	Tat(−) (n = 8)	Tat(+) (n = 10)	Tat(−) (n = 8)	Tat(+) (n = 8)	Tat(−) (n = 8)	Tat(+) (n = 9)
Mean Velocity (m/s)	0.022 ± 0.003	0.018 ± 0.003	0.077 ± 0.013 †	0.089 ± 0.012 †	0.007 ± 0.003	0.004 ± 0.001	0.01 ± 0.004	0.041 ± 0.011 §
Rearing number	34.8 ± 6.6	25.3 ± 6.2	13.8 ± 4.0 †	19.7 ± 4.1 †	1.1 ± 0.6	1.6 ± 0.5	1.4 ± 0.9	2.0 ± 1.2
Rearing Time (s)	23.3 ± 5.6	19.5 ± 5.5	5.2 ± 1.8 †	9.2 ± 2.3 †	0.4 ± 0.3	0.6 ± 0.2	0.6 ± 0.5	1.0 ± 0.6
Latency to first enter dark (s)	30 ± 12	81 ± 32	38 ± 17	8 ± 2 ‡	44 ± 37	38 ± 19	17 ± 9	14 ± 5
Light zone time (s)	116 ± 32	91 ± 25 *	119 ± 25	46 ± 12 *	102± 38	68 ± 19	53 ± 12 †	33± 7 †
Number of transitions	10 ± 2	9 ± 2	17 ± 3 †	11 ± 1 †	10 ± 2	11± 2	15 ± 3	11 ± 2