Table 1.
Typical magnetic resonance imaging contrast agents (MRCAs) clinically approved or in clinical trials.
| Trade Name | Generic Name | Chemical Code | MRI Mode | Clinical Trial | Clinically Approved |
|---|---|---|---|---|---|
| Dotarem/Clariscan | Gadoterate meglumine | Gd-DOTA | T1-weighted | - | Yes |
| ProHance | Gadoteridol | Gd-HPDO3A | T1-weighted | - | Yes |
| Gadovist | Gadobutrol | Gd-DO3A-butrol | T1-weighted | - | Yes |
| Magnevist | Gadopentetate dimeglumine | Gd-DTPA | T1-weighted | - | Yes |
| Omniscan | Gadodiamide | Gd-DTPA-BMA | T1-weighted | - | Yes |
| Optimark | Gadoversetamide | Gd-DTPA-BMEA | T1-weighted | - | Yes |
| Multihance | Gadobenate dimeglumine | Gd-BOPTA | T1-weighted | - | Yes |
| Combidex/Sinerem | Ferumoxtran | Dextran coated SPION | T2-weighted | Yes | - |
| Resovist/Cliavist | Ferucarbotran/Ferrixan | Carboxydextran coated SPION | T2-weighted | - | Yes |
| Feridex I.V./Endorem | Ferumoxide | Dextran | T2-weighted | - | Yes |
| Feraheme/Rienso | Ferumoxytol | Carboxymethyl-dextran coated SPION | T2-weighted | - | Yes |
| Clariscan | Feruglose | PEGylated starch coated SPION | T2-weighted | Yes | - |
| Lumirem/GastroMARK | Ferumoxsil | Siloxane coated SPION | T2-weighted | - | Yes |
| Abdoscan | - | Sulfonated poly (styrene-divinylbenzene) copolymer coated SPION | T2-weighted | - | Yes |