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. 2020 Oct 26;21(21):7948. doi: 10.3390/ijms21217948

Figure 2.

Figure 2

The post-translational modifications of HmgB1. (A) The 3D orientation of modified amino acids of HMGB domains of protein; (B) Schematic representation of the location of HmgB1 modification sites and functionally significant sections of the amino acid sequence of HmgB1. HAVCR2—Hepatitis A virus cellular receptor 2; LPS—lipopolysaccharide; AGER/RAGE—advanced glycosylation end-product specific receptor; NLS—nuclear localization sequence. The figure is based on PDB (1AAB, 2GZK) and the data are described in the following works [11,65,66,67,68,69,70,71].