Table 1.
Time point | Enrolment | Allocation | Post-allocation | ||||||||||
Preoperative | 0 d | T0 | T1 | T2 | T3 | T4 | T5 | T6 | T7 | T8 | T9 | Discharged | |
Enrolment | |||||||||||||
Eligibility screen | X | ||||||||||||
Informed consent | X | ||||||||||||
Allocation | X | ||||||||||||
Interventions | |||||||||||||
TEG-BT | X | X | X | X | |||||||||
T-BT | |||||||||||||
Assessments | |||||||||||||
Demographic data | X | X | |||||||||||
Baseline variables | X | ||||||||||||
HGB | X | X | X | X | X | X | |||||||
Hct | X | X | X | X | X | X | |||||||
PLTs | X | X | X | X | X | X | |||||||
PT | X | X | X | X | X | X | |||||||
APTT | X | X | X | X | X | X | |||||||
INR | X | X | X | X | X | X | |||||||
Fibrinogen | X | X | X | X | X | X | |||||||
Crystalloid fluid | X | ||||||||||||
Artificial colloid fluid | X | ||||||||||||
RBCs | X | ||||||||||||
FFP | X | ||||||||||||
PLTs | X | ||||||||||||
Fibrinogen | X | ||||||||||||
Prothrombin complex | X | ||||||||||||
Albumin | X | ||||||||||||
Blood loss | X | ||||||||||||
Urine output | X | ||||||||||||
The amount of blood lost between 0 and 72 hours after surgery | X | ||||||||||||
Total blood transfusion between 0 and 72 hours after surgery | X | ||||||||||||
The lowest HGB level | X | ||||||||||||
ICU duration | X | ||||||||||||
Overall length of stay | X | ||||||||||||
Total cost of the hospitalisation | X |
T0, entering the operating room; T1, the performance of CRS; T2, before HIPEC; T3, after HIPEC; T4, at the end of surgery; T5, 2 hours after surgery; T6, postoperative day 1; T7, postoperative day 2; T8, postoperative day 3; T9, postoperative day 5.
APTT, activated partial thromboplastin time; FFP, fresh frozen plasma; Hct, haematocrit; HGB, haemoglobin; ICU, intensive care unit; INR, international normalised ratio; PLTs, platelets; PT, prothrombin time; RBCs, red blood cells; T-BT, traditional blood product transfusion; TEG-BT, thromboelastography-guided blood product transfusion.