Table 1.
Inclusion criteria | Exclusion criteria |
1. Documented close contact with a PCR-confirmed SARS-CoV-2 positive individual | 1. Fever (temperature >38.0°C) and/or respiratory symptoms (cough, dyspnoea) and/or new anosmia/ageusia |
2. ≥16 years of age | 2. Individuals with previous confirmed SARS-CoV-2 infection within the last 6 months |
3. Informed consent documented by signature (including parent’s or legal guardian’s signature if the participant is 16 and 18 years old) | 3. Known impairment of liver function |
4. Known hypersensitivity to any of the study medications | |
5. Use of any medications that are contraindicated with LPV/r using the website www.hiv-druginteractions.org/checker | |
6. Individuals on boosted protease inhibitor as part of an antiretroviral therapy | |
7. Inability to be followed-up for the trial period |
LPV/r, lopinavir/ritonavir.