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. 2020 Nov 12;10(11):e040110. doi: 10.1136/bmjopen-2020-040110

Table 1.

Inclusion and exclusion criteria

Inclusion criteria Exclusion criteria
1. Documented close contact with a PCR-confirmed SARS-CoV-2 positive individual 1. Fever (temperature >38.0°C) and/or respiratory symptoms (cough, dyspnoea) and/or new anosmia/ageusia
2. ≥16 years of age 2. Individuals with previous confirmed SARS-CoV-2 infection within the last 6 months
3. Informed consent documented by signature (including parent’s or legal guardian’s signature if the participant is 16 and 18 years old) 3. Known impairment of liver function
4. Known hypersensitivity to any of the study medications
5. Use of any medications that are contraindicated with LPV/r using the website www.hiv-druginteractions.org/checker
6. Individuals on boosted protease inhibitor as part of an antiretroviral therapy
7. Inability to be followed-up for the trial period

LPV/r, lopinavir/ritonavir.