Table 3.
Regression coefficients† for first trimester ln-unit increase in urinary phthalate metabolite concentration associated with McCarthy Scales of Children’s Abilities, stratified by sex †.
| General Cognitive Index | Motor Scale | |||
|---|---|---|---|---|
| Boys n = 77 | Girls n = 90 | Boys n = 77 | Girls n = 90 | |
| Metabolite | ß † (95% CI) | ß † (95% CI) | ß † (95% CI) | ß † (95% CI) |
| HMWP 1 | −3.4 (−7.1, 0.3) | −0.6 (−4.1, 2.9) | −3.2 * (−6.1, −0.4) | −2.5 * (−4.9, −0.2) |
| MEHP | −3.1 (−6.2, 0.1) | −0.1 (−3.1, 3.0) | −3.0 * (−5.4, −0.5) | −1.7 (−3.8, 0.3) |
| MEHHP | −2.1 (−5.0, 0.9) | −0.2 (−3.3, 2.9) | −2.2 (−4.5, 0.1) | −2.2 * (−4.3, −0.1) |
| MEOHP | −2.2 (−5.2, 0.8) | −0.4 (−3.5, 2.7) | −2.3 (−4.6, −0.0) | −2.1 * (−4.2, −0.0) |
| MECPP | −2.7 (−6.5, 0.9) | −0.2 (−3.8, 3.4) | −2.4 (−5.3, 0.5) | −2.4 * (−4.8, −0.0) |
| MBzP | −2.5 * (−4.9, −0.1) | −1.3 (−3.6, 1.0) | −2.3 * (−4.2, −0.5) | −0.5 (−2.0, 1.1) |
| MCPP | −1.9 (−5.9, 2.2) | 0.3 (−2.5, 3.2) | −1.9 (−5.1, 1.2) | −0.5 (−2.4, 1.5) |
| ∑ DEHP 2 | −3.1 (−6.8, 0.5) | −0.3 (−3.8, 3.2) | −2.9 * (−5.7, −0.1) | −2.5 * (−4.8, −0.2) |
† Adjusted for gestational age, breastfeeding and maternal IQ. 1 High-Molecular-Weight Phthalate Molar Sum: MEHP, MEHHP, MEOHP, MECPP, MBzP and MCPP. 2 Molar Sum of the four metabolites derived from DEHP: MEHP, MEHHP, MEOHP and MECPP. * p < 0.05.