Table 1.
Baseline demographics characteristics.
| Enbrel→Humira | Humira→Enbrel | p-value | |
|---|---|---|---|
| (n = 9) | (n = 9) | ||
| Age (years)a | 39.44 ± 11.20 | 36.00 ± 7.57 | 0.456 |
| Sex (male %) | 5 (55.56%) | 7 (77.78%) | 0.720 |
| NSAIDs (%) | 8 (88.9%) | 6 (66.7%) | 0.576 |
| DMARDs(%) | 8 (88.9%) | 6 (66.7%) | 0.294 |
| Weight (kg)b | 59.00 (17.00) | 61.00 (16.00) | 0.544 |
| Height (cm)a | 164.00 ± 11.54 | 165.00 ±6.95 | 0.827 |
| SBP (mmHg)a | 130.40 ± 15.56 | 116.30 ± 14.18 | 0.062 |
| DBP (mmHg)a | 76.22 ± 11.33 | 75.00 ± 8.40 | 0.798 |
| MBP (mmHg)a | 94.29 ± 12.05 | 88.78 ± 8.12 | 0.272 |
| WBC (103/μl)a | 7.19 ± 2.71 | 7.06 ± 0.75 | 0.896 |
| RBC (104/μl)a | 460.00 ± 52.88 | 481.70 ± 57.20 | 0.416 |
| Hb (gm/dl)a | 13.29 ± 1.50 | 12.71 ± 1.65 | 0.449 |
| Ht (%)a | 40.67 ± 3.88 | 39.84 ± 3.70 | 0.652 |
| MCV (fl)b | 88.20 (6.70) | 86.20 (5.30) | 0.345 |
| MCH (Pg)b | 28.70 (3.90) | 28.20 (2.40) | 0.345 |
| MCHC (g/dl)b | 32.60 (0.60) | 32.50 (1.10) | 0.462 |
| Platelet (103/μl)a | 264.56 ± 54.19 | 250.00 ± 73.03 | 0.638 |
| GPT (IU/l)b | 14.00 (6.00) | 13.00 (10.00) | 1.000 |
| Creatinine (mg/dl)a | 0.83 ± 0.10 | 0.84 ± 0.17 | 0.870 |
| HS-CRP (mg/dl3)b | 0.84 (2.95) | 0.26 (0.53) | 0.728 |
| ESR (mm/h)b | 16 (28) | 18 (20) | 0.862 |
| IgAb | 222.00 (55.00) | 255.00 (224.00) | 0.862 |
| PGAa | 6.06 ± 1.98 | 4.44 ± 1.24 | 0.055 |
| PtGAa | 5.67 ± 2.24 | 4.67 ± 2.65 | 0.399 |
| BASDAIa | 4.67 ± 2.71 | 4.25 ± 2.84 | 0.752 |
| BASFIb | 2.40 (3.35) | 5.30 (1.50) | 0.303 |
| BAS-Ga | 4.95 ± 3.03 | 5.17 ± 2.59 | 0.873 |
| ASDAScrp | 2.02 ± 1.34 | 2.05 ± 1.38 | 0.971 |
| ASDASesr | 1.53 ± 0.99 | 1.61 ± 1.04 | 0.865 |
mean ± SD.
median (IQR).
NSAIDs, non-steroidal anti-inflammatory drugs; DMARDs, disease-modifying antirheumatic drugs; SBP, systolic blood pressure; DBP, diastolic blood pressure; MBP, mean blood pressure; WBC, white blood count; RBC, red blood count; Hb, hemoglobin; Ht, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin; GPT, alanine aminotransferase; HS-CRP, hypersensitive C-reactive protein; ESR, erythrocyte sedimentation rate; PGA, Physician Global Assessment; PtGA:Patient Global Assessment; BASDAI, Bath Ankylosing Spondylitis Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; BAS-G, Bath Ankylosing Spondylitis Patient Global Score; ASDAS, Ankylosing Spondylitis Disease Activity Score.