Table 1.

List of purine metabolism-related genes among differently expressed genes in the liver and their differences between model control and allopurinol groups or model control and urolithin A high dose groups.

Gene Symbol	Gene Name	Fold Change (MC vs. AL)	Fold Change (MC vs. UH)	Molecular Function
Prps1l3	phosphoribosyl pyrophosphate synthetase 1-like 3	0.73 *	0.70 *	Converts ribose 5-phosphate into phosphoribosyl pyrophosphate (PRPP) [23]
Entpd4	ectonucleoside triphosphate diphosphohydrolase 4	0.84 **	0.76 **	Catalyzes the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner [24]
Ak4	adenylate kinase 4	0.78 **	0.76 **	Catalyze the reversible transfer of the terminal phosphate group between ATP and AMP [25]

Table values are expressed as mean ± SEM for three mice in each group. * p < 0.10, ** p < 0.05 in comparison to model control mice.