Abbreviations and symbols of quantities	Unit	Definition
C-container		Container with demineralized water intended to cool off a target volume.
Demi-water		Demineralized water.
IRE		Irreversible electroporation.
IPE		Irreversible permeabilization effect (we chose IPE instead of IRE effect to distinguish between only the permeabilization effect, and the permeabilization and the thermal effects jointly produced by IRE).
H-container		Container with demineralized water intended to heat a target volume.
HF-IRE		High-frequency irreversible electroporation.
HyCHEED		Hydraulically controllable heat exchange electroporation device.
NA		Not applicable.
Post-treatment σav	[S·m−1]	Average electrical specific conductivity of a target volume that is measured after the treatment.
T-holder		Target holder.
TV		Target volume.
E	[V·m−1] or [V·cm−1]	Electric-field vector.
J	[A·m−2]	Electric-current density.
J · E	[W·m−3]	The Joule Heating term; the heat generation rate per unit volume.
cp	[J·kg−1·°C−1]	Specific heat capacity of a medium.
d	[m]	Distance between electrode plates of an electroporation cuvette.
fP	[Hz]	Pulse frequency.
HV	[W·m−3·°C−1]	Volumetric heat transfer coefficient between the target volume and its direct ambiance.
t	[s] or [min]	Time.
t0, t1, …, t5	[min]	Time points.
tinit	[s]	Initial time at which irreversible electroporation treatment starts.
tP	[s]	Pulse duration.
σ	[S·m−1]	Electrical specific conductivity of a target volume.
σav	[S·m−1]	Average electrical specific conductivity of a target volume.
A	[m2]	Surface of a target volume that is contacting the electrode plate of an electroporation cuvette.
E = |E |	[V·m−1] or [V·cm−1]	Magnitude of an electric-field vector.
EIRE(th)	[V·m−1]	Electric-field threshold of irreversible electroporation; minimum electric-field value that ablates target cells/tissue during the irreversible electroporation.
I	[A]	Measured electric current.
SD		Standard deviation.
T	[°C]	Temperature.
Ttarget	[°C]	Target temperature.
TA	[°C]	Temperature of the direct ambient of the target volume.
Tav	[°C]	Average temperature evolution over time.
Φ	[V]	Measured voltage.