TABLE 2.

Antibiotic consumption as mean DDD per 1,000 inhabitants per day (DDD/1,000/D) from 2017 to 2019 by antibiotic class.

Rank	Substance	ATC code	Mean DDD/1,000/D ± SD
J01—antibacterials for systemic use
1	Doxycycline	J01AA02	20.01 ± 24.529
2	Amoxicillin	J01CA04	16.759 ± 19.538
3	Trimethoprim-sulfamethoxazole	J01EE01	12.422 ± 6.851
4	Erythromycin	J01FA01	7.159 ± 2.027
5	Ciprofloxacin	J01MA02	4.616 ± 3.058
6	Azithromycin	J01FA10	2.711 ± 0.311
7	Norfloxacin and tinidazole	J01RA13	2.265 ± 0.31
8	Combinations of penicillins	J01CR50	1.33 ± 0.337
9	Procaine benzylpenicillin	J01CE09	0.953 ± 1.144
10	Phenoxymethylpenicillin	J01CE02	0.808 ± 0.816
11	Levofloxacin	J01MA12	0.707 ± 0.466
12	Tetracycline	J01AA07	0.655 ± 0.732
13	Amoxicillin and beta-lactamase inhibitor	J01CR02	0.452 ± 0.105
14	Benzylpenicillin	J01CE01	0.414 ± 0.646
15	Ceftriaxone	J01DD04	0.372 ± 0.049
16	Ampicillin	J01CA01	0.252 ± 0.345
17	Cefalexin	J01DB01	0.241 ± 0.164
18	Chloramphenicol	J01BA01	0.194 ± 0.044
19	Cefixime	J01DD08	0.101 ± 0.045
20	Ampicillin and beta-lactamase inhibitor	J01CR01	0.087 ± 0.123
J04—antimycobacterials
1	Rifampicin and isoniazid	J04AM02	1.458 ± 1.657
2	Isoniazid	J04AC01	0.752 ± 0.297
3	Ethambutol	J04AK02	0.017 ± 0.021
4	Pyrazinamide	J04AK01	0.01 ± 0.017
5	Rifampicin	J04AB02	0 ± 0
6	Clofazimine	J04BA01	0 ± NA
P01AB—nitroimidazole antiprotozoal agents
1	Metronidazole (parenteral)	P01AB01	5.248 ± 1.723
2	Tinidazole	P01AB02	0.387 ± 0.231
3	Secnidazole	P01AB07	0.024 ± 0.005
4	Ornidazole	P01AB03	0.007 ± 0.013

ATC, Anatomical Therapeutic Chemical; DDD, defined daily doses.