PRR |
Pattern recognition receptors |
PAMPS |
Pathogen-associated molecular patterns |
DAMPS |
Danger-associated molecular patterns |
DUB |
Deubiquitinating enzyme |
KC |
Kupffer cell |
TLR |
Toll-like receptors |
RIG-I |
Retinoic acid-inducible gene I |
RLR |
RIG-I- like receptors |
MDA5 |
Melanoma-differentiation-associated gene 5 |
NOD |
Nucleotide-binding oligomerization domain |
NLR |
NOD-like receptors |
IFN |
Interferons |
IL |
Interleukin |
AIM2 |
Absent in melanoma 2 |
NLRP3 |
Nucleotide-binding oligomerization domain leucine-rich repeat and pyrin domain-containing protein 3 |
ASC |
Apoptosis-associated speck-like protein containing a caspase activating and recruitment domain |
CARD |
Caspase activation and recruitment domains |
VSV |
Vesicular stomatitis virus |
TRIM25 |
Tripartite motif containing 25 |
MAVS |
Mitochondrial antiviral-signaling protein |
NF-κB |
Nuclear factor-κB |
TRAF |
Tumor necrosis factor receptor-associated factor |
IKK |
Inhibitor of nuclear factor κB kinase |
TBK1 |
Tank-binding kinase 1 |
IRF |
IFN regulatory factor |
CHIP |
C-terminus of Hsc70 interacting protein |
RNF |
RING-finger protein |
STING |
Stimulator of IFN genes |
LUBAC |
Linear ubiquitin assembly complex |
TAX1BP1 |
Tax1-binding protein 1 |
ISRE |
IFN-stimulated response element |
MyD88 |
Myeloid differentiation primary response 88 |
TIR |
Toll/Interleukin-1 receptor |
TRIF |
TIR-domain-containing adapter-inducing interferon-β |
IRAK |
IL-1R-associated serine/threonine kinases |
TNFR1 |
TNF receptor-1 |
EV71 |
Enterovirus 71 |
MNV 1 |
Murine norovirus 1 |
FBXO3 |
F-box protein 3 |
BRCC3 |
BRCA1/BRCA2-containing complex 3 |
BRISC |
BRCC36 isopeptidase complex |
EMPs |
Erythromyeloid progenitors |
HSCs |
Hematopoietic stem cells |
IPS-1 |
Interferon-beta promoter stimulator 1 |
ISG |
Interferon stimulating genes |