. 2020 Oct 29;21(21):8066. doi: 10.3390/ijms21218066

Table 3.

The top 5% residues showing the highest average BC values. All residues with known functions are in bold and interface residues are italicized.

CA	Residues
CmCA	Chain A: *Asn53^h, Asn122, Glu132, Ile144, Val146^c, Ala148, Asn197, Glu207^h, Gly208, Val209^c, Trp211*^c, Ile247
CmCA	Chain B: *Asn53^h Ile57, Asn122, Glu132, Val146* ^c, Ala148, *Phe196, Asn197, Ser199, Glu207* ^h, *Val209* ^c
GEprmCA	Chain A: *Arg48, Asn114, Glu124, Asn135, Val138^c, Ser140, Phe188, Val201^c, Ile202, Trp203^c, Arg238*
GEprmCA	Chain B: *Arg48, Val53, Ile96, Asn114, Glu124, Asn135, Val138 ^c, Ser140, Val201^c, Trp203^c, Ala237, Arg238*
GHr1CA	Chain A: *Asn38^h, Glu113, Asn124, Val127^c, Ser129, Phe177, Asn178, Gln188^h, Trp192^c, Arg227*
GHr1CA	Chain B: *Asn38^h, Val42, Asn103, Glu113, Val127^c, Ser129, Asn178, Gly189, Val190^c, Trp192^c, Leu224, Ala226, Arg227*^h
HtCA	Chain A: *Asn54^h, Glu130, His132^z, Val144^c, Asn196, Ser198, Thr200^p, Glu206^h, Val208^c, Trp210*^c
HtCA	Chain B: *Asn54^h, Glu130, His132^z, Val144^c, Ala146, Asn196, Ser198, Glu206^h, Val208^c, Trp210^c, Arg245*^h, Ile247
LOGACA	Chain A: *Asn59^h, Asp107, His136^z, Val148^c, Ser198, Ser200, Cys206^d, Gly209,Val210^c, Ala246^h, Arg247*
LOGACA	Chain B: *Asn59^h, Val63, His124, Glu134, Val148^c, Tyr197, Ser200, Gly209, Val210^c,Trp212^c, Arg247*
NtCA	Chain A: Gln58, Val61, Asn122, Glu132, Glu143, Val146^c, Ala148, *Tyr196, Val209^c, Trp211^c, Arg245*^h
NtCA	Chain B: *Asn57^h, Val61, Asn122, Glu143, Val146^c, Ala148, Asp197, Val209^c, Trp211^c, Leu242, His243, Arg245*^h
PhCA	Chain A: *Asn52^h, His117, Glu127, Val141^c, Ser192, Ser194, Thr196^p, Cys200^d, Glu202^h, Val204^c, Asn239, Arg2410*^h
PhCA	Chain B: *Asn52^h, Glu127, Val141^c,Tyr191, Ser194, Glu202^h, Gly203, Val204^c, Arg241*
PmCA	Chain A: *Asn49^h, Val53, His114, Glu124, Val138^c, Ser189, Ser191, Cys197^d, Val201^c, Ala237*,
PmCA	Chain B: *Asn49^h, Val53, Ile55, His114, Glu124, Val138* ^c, *Ser189, Ser191, Cys197* ^d,Glu199 ^h, *Gly200, Val201* ^c
SlCA	Chain A: Glu129, Val143^c, Ala145, *Arg192^h, Phe193, Asn194, Ser196, Val206^c, Trp208^c, Arg243*^h
SlCA	Chain B: *Asn53^h, Ile57, Asn119, Leu128, Glu129, Val143^c, Ala145, Asn194, Val206^c, Trp208^c, Arg243^h, Val244*^h, Val245
SNbcCA	Chain A: *Asn53^h, Ile57, Glu129, His131^z, Val143 ^c, Ala145, Asn194, Ser196, Glu204, Val206^c, Trp208^c, Arg243*^h
SNbcCA	Chain B: *Gly51, Asn53^h, Glu129, Val143^c, Ala145, Phe193, Asn194, Val206^c, Trp208^c, Arg243*
SrCA	Chain A: *Asn54^h, Ile58, Asn120, Glu130, Val144^c, Ala146, Phe193, Glu204^h, Val206^c, Trp208^c, Arg243*
SrCA	Chain B: *Asn54^h, Glu130, Val144^c, Ala146, Asn194, Ser196, Glu204^h, Val206^c, Trp208^c, Arg243*^h
TaCA	Chain A: Ile58, *Ser60, Ala63, Val64^h, Lys65, Cys67^d, Leu68, His119, Val143^c, Gly145, Tyr191, Arg192^h, Val206^c, Ile209, Lys247*
	Chain B:Val64^h, *Lys65, Cys67^d, Leu68, Gly145, Tyr190, Tyr191, Arg192^h, Tyr193, Val206^c, Trp208^c, Ile209, Lys247*
	Chain C: Ile58, *Val64^h, Lys65, Cys67^d, Leu68, His119, Gly145, Tyr191, Arg192^h, Arg243^h, Lys247*
	Chain D: *Val64^h, Lys65, Cys67^d, Leu68, Tyr190, Tyr191, Arg192^h, Val206^c, Lys247*
VACA1	Chain A: Thr45, Ile51, Asn112, Glu122, His124^z, Val136^c, Ser138, *Phe185, Asn186, Val198^c, Trp200^c, Ala233^h, Arg234*^h
VACA1	Chain B: Ile51, Asn112, Val136^c, *Phe185, Asn186, Ser188, Val198^c, Trp200^c, Ala233^h, Arg234*^h
VaCA2	Chain A: Val135^c, Ala137, *Arg183^h, Phe184, Gly196, Val197^c, Trp199^c, Met234*^h
VaCA2	Chain B: *Gln45, Asn46, Ile50, Ile52, Asn111, Glu121, Val135^c, Ala137, Phe184, Asn185, Trp199^c, Asn231, Ala23^h, Arg233, Met234*^h, Val235
VdCA	Chain A: Ile50, Asn111, Glu121, Val135^c, Ala137, *Phe184, Asn185, Val197^c, Trp199^c, Ala232^h, Arg233*^h
VdCA	Chain B: *Asn46^h, Ile50, Asn111, Glu121, Val135^c, Ala137, Phe184, Asn185, Val197^c, Trp199^c, Arg233*^h

^h Hotspot residues; ^z Active site His residue; ^c CO₂ binding pocket residue; ^d Cys–Cys disulfide bond residue; ^p proton shuttling residues.