Table 3.

Apparent permeability coefficients (P_app) (cm/s) and cumulative permeable percentage of PR, PEG4k-PR, and PEG5k-PR.

	Conc.	Jejunum		Ileum		Colon
	(μM)	Papp (×10−6 cm/s)	W (%)	Papp (×10−6 cm/s)	W (%)	Papp (×10−6 cm/s)	W (%)
P	28	7.68 ± 2.04	4.44 ± 1.98	6.17 ± 2.17	3.55 ± 1.50	4.07 ± 1.33	2.50 ± 0.82
	56	8.36 ± 3.11	4.92 ± 1.12	6.77 ± 2.32	4.23 ± 1.38	5.83 ± 1.9	3.36 ± 0.79
	112	10.42 ± 2.58	5.77 ± 1.70	8.90 ± 1.65	5.27 ± 2.31	8.57 ± 3.54	5.18 ± 1.22
PEG4k-PR	28	0.87 ± 0.15	0.81 ± 0.11	0.61 ± 0.13	0.32 ± 0.05	ND *	ND *
	56	0.83 ± 0.21	0.55 ± 0.07	0.66 ± 0.37	0.42 ± 0.13	0.51 ± 0.08	0.36 ± 0.05
	112	1.36 ± 0.32	0.54 ± 0.1	0.97 ± 0.28	0.63 ± 0.19	0.65 ± 0.14	0.44 ± 0.13
PEG5k-PR	28	0.55 ± 0.16	0.39 ± 0.15	0.69 ± 0.13	0.42 ± 0.16	ND *	ND *
	56	0.60 ± 0.08	0.37 ± 0.07	0.57 ± 0.28	0.36 ± 0.10	0.39 ± 0.07	0.24 ± 0.04
	112	0.54 ± 0.23	0.35 ± 0.08	0.61 ± 0.16	0.39 ± 0.04	0.41 ± 0.18	0.25 ± 0.07

* Not detected.