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. 2020 Nov 1;21(21):8192. doi: 10.3390/ijms21218192
ADC antibody–drug conjugate
ADCC antibody-dependent cellular cytotoxicity
ADP antibody-dependent phagocytosis
APC antigen-presenting cell
BCMA B-cell maturation antigen
belamaf belantamab mafodotin
BiAb bispecific antibody
BiTE bispecific T-cell engager
CDC complement-dependent cytotoxicity
CRS cytokine release syndrome
CTLA-4 cytotoxic T-lymphocyte antigen 4
d, dex dexamethasone
Dara daratumumab
di-scFv bivalent single-chain variable fragment
Elo elotuzumab
EMA European Medicines Agency
Fab fragment antigen binding
Fc fragment crystallizable region
FDA US Food and Drug Administration
G grade
Ig immunoglobulin
IMiDs immunomodulatory drugs
IRR infusion-related reaction
Isa isatuximab
iv intravenous
K carfilzomib
mAb monoclonal antibody
MAC membrane attack complex
MDSC myeloid-derived suppressor cell
MM multiple myeloma
MMAF monomethyl auristatin F
MRD minimal residual disease
NA not available
NDMM in newly diagnosed (ND) MM
NK natural killer cell
NR not reached
NTE non-transplant-eligible
ORR overall response rate
OS overall survival
P, Poma pomalidomide
PD-1 programmed cell death protein 1
PD-L1 programmed death ligand 1
PFS progression-free survival
PI proteasome inhibitor
R lenalidomide
RRMM relapsed/refractory multiple myeloma
sc subcutaneous
scFv single-chain variable fragment
sCR stringent complete response
SLAMF7 signaling lymphocytic activation molecule family 7
T thalidomide
TE transplant-eligible
Treg regulatory T cell
V bortezomib
VMP bortezomib-melphalan-prednisone