Figure 6.

Effects of BMP-2 and FGF-2 on bone marrow cell populations. Collagen pellets containing BMP-2 (10 µg) or FGF-2 (10 µg) or DW (control) were transplanted into mouse femur defects and samples were analyzed by FCM at 5 days (A) and 14 days (B) after transplantation. HSCs: Lin⁻Sca-1⁺c-Kit⁺CD150⁺CD48⁻, Erythroid cells: Ter119⁺, Myeloid cells: CD11b⁺Gr-1⁺, B cells: B220⁺, T cells: CD3⁺, Leptin R⁺ stromal cells: CD45⁻Ter119⁻CD31⁻LepR⁺ (n = 4–11, * p < 0.05, ** p < 0.01, *** p < 0.001 versus control pellet (#). One-way ANOVA/Tukey).