T1D	type 1 diabetes mellitus
T2D	type 2 diabetes mellitus
IFN	interferon
IL	interleukin
TNF	tumor necrosis factor
MCP-1	monocyte chemoattractant protein-1
M1-macrophages	classically activated M1 macrophages
SJW	St. John’s wort
HPF	hyperforin
HYP	hypericin
STAT	signal transducer and activator of transcription
NF-κB	nuclear factor kappa-light-chain-enhancer of activated B cells
JAK	receptor-associated Janus kinases
IkB	inhibitor molecules
IKK	protein kinase complex
iNOS	inducible nitric oxide synthase
MAPKs	mitogen-activated protein kinases
ERK	extracellular signal-related kinase
JNK	c-jun N-terminal kinase
ROS	reactive oxygen species
RNS	reactive nitrogen species
ER	endoplasmic reticulum
CHOP	C/EBP homologous protein
DP5	death protein 5
NSAIDs	non-steroidal anti-inflammatory drugs
AMPK	adenosine monophosphate-activated protein kinase
SOCS3	suppressor of cytokine signaling 3
DCHA-hyperforin	hyperforin dicyclohexylammonium salt
5-LO	5-lipoxygenase
COX	cyclooxygenase
PGE2	prostaglandin E2
fMLP	N-formyl-methionyl-leucyl-phenylalanine
LPS	lipopolysaccharide
PMN	polymorphonuclear neutrophils
PXR	pregnane X receptor
RXR	retinoid X receptor
HFD	high-fat-diet
AD	Alzheimer’s disease
SOD	superoxide dismutase
Aβ	amyloid-β-peptide
AAP	amyloid precursor protein
AST	aspartate aminotransferase
ALT	alanine aminotransferase
ICAM	intercellular cell adhesion molecule
BCL-2	B-cell lymphoma protein 2
BAX	B-cell lymphoma protein 2 (Bcl-2)-associated X
CXCL	C‑X‑C motif chemokine ligand
CIITA	immune-transcriptional co-activator
Puma	p53-upregulated mediator of apoptosis
Bim	B-cell lymphoma 2 interacting mediator of cell death
Chop	C/EBP homologous protein
PDX-1	pancreatic duodenal homeobox-1
FFA	free fatty acids
IAPP	islet amyloid polypeptide
FATP1	transporter of free fatty acids
HYP	hypericin
HFHS	high-fat/high-sucrose
NAFLD	non-alchoholic liver fatty disease
pAMPK	phosphorylated adenosine monophosphate-activated protein kinase
PKACs	protein kinase A catalytic
CRP	C reactive protein
TG	triglycerides
LDL	low-density lipoprotein
PKA	protein kinase cAMP-dependent
TGF-β	transforming growth factor beta
TRPC6	transient receptor potential channel
GABA	gamma-aminobutyric acid
NMDA	N-methyl-d-aspartate
PPAR-γ	peroxisome proliferator-activated receptor-gamma
STZ-NA	streptozotocin-nicotinamide
AGE	advanced glycation end products
TLR	Toll-like receptor
CYPs	cytochromes P450s
P-gp	P-glycoprotein
cAMP	cyclic adenosine monophosphate
PTP1B	protein tyrosine phosphatase 1B