Figure 5.

Effects of PDIA3 silencing on IL6, IL1β, and COX2 in activated human GB cells: T98G cells were treated or not with TII (TNFα, IL1β, and hIFNγ) for 8 h, and detection of transcripts was performed by qRT-PCR. Results indicate relative IL6 (A), IL1β (B), and COX2 (C) mRNA expression in TII-treated cells compared to untreated cells (control or silenced cells, to which the value of 1 was attributed) and are the mean ± SEM of three independent determinations. Statistically significant differences between TII-treated control andPDIA3-silenced cells are shown. **** p < 0.0001.