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. 2020 Oct 30;21(21):8142. doi: 10.3390/ijms21218142

Figure 4.

Figure 4

Effects of the local administration of 1 μM tetrodotoxin (TTX) and 100 μM CBX into the OFC on basal L-glutamate release in the OFC of S286L-TG after FCHK-evoked stimulation. The perfusion medium in the OFC was switched to MRS, with or without (control: post-stimulation: gray column) 1 μM TTX (red column) or 100 μM CBX (blue column). The ordinate AUC of the extracellular L-glutamate level (nmol) for 60 min during perfusion of MRS with or without TTX or CBX is shown. ** p < 0.01, relative to the control (pre-stimulation), and @@ p < 0.01, relative to the control (post-stimulation) by a one-way analysis of variance (ANOVA) with Tukey’s multiple comparison. The F-values of the L-glutamate level in the OFC, according to the one-way ANOVA, are F(3,20) = 9.6 (p < 0.01).