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. 2020 Oct 30;21(21):8142. doi: 10.3390/ijms21218142

Figure 7.

Figure 7

Effects of subacute administration of an increase in the extracellular K+ level on Cx43 expression in the plasma membrane fraction of primary cultured astrocytes (A). Effects of the inhibitor of Erk (FR180204) and Akt (10-DEBC) on K+-dependent Cx43 expression in the plasma membrane (B). Ordinate: mean ± SD (n = 6) of the relative protein level of Cx43. Concentration-dependent effects of extracellular K+ on Cx43 expression in the plasma membrane fraction of the primary cultured astrocytes were analyzed by a one-way ANOVA (@@ p < 0.01 vs. control). The effects of 20 μM FR180204 and 10 μM 10-DEBC on Cx43 expression in the plasma membrane fraction were analyzed by a Student’s t-test (** p < 0.01 vs. 10 mM K+).