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. 2020 Nov 9;6(11):e05434. doi: 10.1016/j.heliyon.2020.e05434

Figure 6.

Figure 6

Overexpression of miR-130a-3p decreases the proliferation and anchorage independent growth in the TNBC cells. (a) MTT test in the TNBC cells transfected with miR-130a-3p, scramble, or non-transfected cells. Data are presented as mean ± SD for three independent experiments; One-way ANOVA followed by Tukey's post-hoc test was used for comparison between groups; (∗p < 0.05, and ∗∗P ˂ 0.01 against blank). (b) The soft agar colony formation assay in the TNBC cells transfected with miR-130a-3p, scramble-miRNA, and non-transfected cells. Data are presented as mean ± SD for three independent experiments (∗p < 0.05, ∗∗P ≤ 0.01, ∗∗∗P ≤ 0.001). miR-130a-3p: cells transfected with miR-130a-3p miRNA Mimic; Scramble: cells transfected with scramble miRNA; Blank: non-transfected cells.