Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(a) Design of a C2-symmetric trans-cyclooctene enabling directed tautomerization and enhanced elimination for fast and complete cleavage irrespective of the click orientation. (b) Synthesis of bis-axial and bis-equatorial C2TCO-diol (11) and overlay of schematic 13C NMR spectra of the separated and purified compounds, which indicate C2-symmetry of both isomers resulting from the rigid “crown” (or twist) conformation of the TCO core structure.
