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PP2 inhibits kidney inflammation in the LPS-induced AKI mice. (A–C) The mRNA levels of inflammation markers such as TNF-α, iNOS, and ICAM1 in kidney tissue were measured using real time RT-PCR analysis. The levels of mRNA were normalized with 18S. (D,E) Paraffin-embedded kidney sections were stained with anti-F4/80 antibody (1:400; original magnification: 200×; scale bar: 100 μm). Data are presented as mean ±SE of 6–8 mice. * p < 0.05 vs. control, † p < 0.05 vs. LPS.
