Table 1.
Classification | Integrin | GP Nomenclature | Ligands |
---|---|---|---|
β1-class | α2β1 | GPIa/IIa | collagen |
α5β1 | GPIc/IIa | fibronectin | |
α6β1 | GPIc‘/IIa | laminin | |
β3-class | αIIbβ3 | GPIIb/IIIa | fibrinogen, fibronectin, thrombospondin, vitronectin, von Willebrand factor |
αvβ3 | GPαv/IIIa | vitronectin, fibrinogen, fibronectin, collagen, osteopontin, thrombospondin, von Willebrand factor |